Ancient regulatory logic

Yao et al. found that certain brain enhancers were functionally conserved between mice (left) and acorn worm (right), despite very limited sequence conservation.

Yao et al. found that certain brain enhancers were functionally conserved between mice (left) and acorn worm (right), despite very limited sequence conservation. {credit}Douglas Epstein{/credit}

A study published this week in Nature Genetics shows that enhancers can be conserved across very long evolutionary distances, even without extensive sequence conservation. Continue reading