Optogenetics, an approach in which cells engineered to express light-sensitive receptors are stimulated with a light source, has enabled important studies of neuronal activity. John Rogers, Robert Gereau and colleagues report the development of miniaturized devices made out of soft and stretchable materials and show they are fully implantable in mice. These tiny devices have an antenna that can receive radio power wirelessly and use it to activate LED lights, stimulating nearby neurons. They are also biocompatible and can interface with peripheral nerves and the spinal cord, which had previously been a challenge. The above image relates to the paper by Rogers, Gereau and colleagues, available now by clicking here.
Monthly Archives: November 2015
Doubling Feed and Food in Brazil
In my previous posts I wrote that Brazil can double its food and feed production without increasing deforestation or further depleting our biomes. I mentioned that Brazil has conservatively 30 million hectares of degraded pasture distributed mostly in the Cerrado area in the south. This is almost the same acreage that Brazil uses for its production of grain and meat in these areas. Today Brazil produces close to 200 million tons of grain and we are the world’s No. 1 meat producer.
However in order for these degraded pastures to recover, EMBRAPA developed a technology that integrated grain production, meat production and forestry. These three components have important roles, and, when integrated correctly, can contribute to the reduction of the greenhouse gases (CO2, methane) that add to global warming.
It would be economically impossible for farmers or the private sector to pay for the recovering of degraded pasture without integrating this effort. The idea is to mix the planting of grain and cattle pasture. First, plant Brachiaria brizantha, which improves the quality of the soil for soybean and corn, which annually are grown in sequence. After three years, convert the land for pasture use, over a period of 1 to 3 years, to receive cattle, which in a degraded pasture would produce almost twice as methane.
The goal is to recover the pasture, because meat generates more revenue for the farmer than grain, and recovered pasture allows for more cattle per area. Yet the grain cycle is equally important, and the shrubbery in the pastures, mainly Eucalyptus, also contributes by converting CO2. Many farms have degraded pasture that has been recovered this way. Using this method, Brazil can be the top producer of feed and food in a couple of decades, and will not increase deforestation.
Luiz Antonio Barreto de Castro
Events
Events with an entrepreneurial bent for November-December. Off you go.
BIO IP Counsels Committee Conference • November 16-18, The Umstead Hotel and Spa, Cary, North Carolina
BLT15 — Biolatam 2015 • November 16-17, Centro Parque, Santiago, Chile
Pantheon 2015 • November 17, San Francisco Marriott Marquis
Biotech 101 for Non-Scientists • December 2-3, MassBio, Cambridge, Massachusetts
California Life Science Academy • December 3-4, Villagio Inn & Spa, Yountville, California
Enforcement, Litigation & Compliance • December 9-10, Renaissance DuPont Circle, Washington DC
The Art of the Alliance Management: Tools and Techniques • December 9, California Life Sciences Association, S. San Francisco
Your input needed on rethinking US regulation
With little fanfare back in the summer, the US Science and Technology Policy Office (OSTP) issued a request for information (RFI) on the need to update the US oversight of biotech products. The last time the Coordinated Framework for the Regulation of Biotechnology (51 FR 23302; June 26, 1986) was updated was in 1992 when technology, to put it mildly, looked a little different.
There have been one or two fundamental advances in bioengineering technology since that time as well, not least RNAi and CRISPR-Cas9. The OSTP’s RFI solicits input on potential inefficiencies/gaps in the Coordinate Framework overseen by the three major agencies—the US Environmental Protection Agency (EPA), the US Food and Drug Administration (FDA), and the US Department of Agriculture (USDA). It is hoped that this consultation process will lead to more streamlined regulation and ensure that the federal biotech regulatory system is prepared for the biotech products of the 21st century.
To accomplish this, a Biotechnology Working Group will be set up to develop an overarching strategy. This will gather feedback from the community and commission an external, independent report to identify both new risks arising from biotechnologies and areas where risks are well understood. The first meeting describing this happened last week. Nature Biotechnology encourages its readers to post comments on the White House site. Readers interested in doing so should be aware of the deadline of November 15.


