Gauging Greek Biopharma

employed

How did employment in Greece affect the economic collapse?

Continuing our analysis of Greece’s economic collapse and its biopharma sector (our first post can be seen here), we’re going to look at Greek employment figures. Between 2005-2011, the number of researchers employed in the overall public sector grew markedly:  up 40.7% in government institutes and 12.7% in universities over the period.

Consider that over the same period the number of people employed in small and medium enterprises (SMEs) of any kind fell by 29% and R&D investment by these SMEs increased by 26.5% (though in Greece, ‘R&D’ can include all sorts of business development expenses).

Taken together, these figures suggest the private sector adapted early to the crisis, choosing to focus in on a few promising research programmes but cutting wider, less-necessary staff. This was in contrast to the public sector, where policies make it nearly impossible to lay off workers. This is part of a broad public sector inertia, which also includes a lack of political will to implement market-driven competitiveness measures. In hindsight, the government should have followed the example set by the private sector and made targeted cuts, which, while initially reducing the workforce and hurting Greek families, could have reduced a financial burden on the national economy and perhaps staved off the complete collapse. After all, if restructuring and targeted cuts are occasionally necessary for a private company to remain competitive, structural reforms at the state level in Greece could help the country compete and regain entry into international markets. Instead in 2010, there were across-the-board austerity measures.

How has this left the biopharma sector in Greece? It was impacted less significantly than the overall Greek economy. Today the Greek biotech world is generally divided into three subsectors. First are underfunded universities and research centers, which suffer from all of the problems of the public sector described above, and which lack an overall national research strategy and priorities. Second are profitable, Greek-owned pharma companies that make money from generics, including selling to the developing world, but which generally do not make any sizable R&D investment and conduct their bioequivalence studies abroad. Third are profitable, import companies, focused on established brands and either selling locally or exporting to Southeast Europe or the Middle East.

It is this third category that has suffered most, as their livelihood is dependent on timely payments from hospitals – something that happened less and less frequently during the economic crisis. Yet even this subsector is in better shape than Greece as a whole.

Iordanis Arzimanoglou

Athina Ikonomidou

The Problem with Greece

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The public purse.

Greece’s economic crisis that started at the end of 2009 – which has increased unemployment from 10% (2009) to 27.5% (last quarter of 2013), and decreased GDP in millions of euros from 231.081 (2009) to 182.054 (2013) – has had a moderate negative impact on the country’s R&D and its ability to innovate, compared to other sectors. Spending on research and innovation is stuck at around 0.5%. Given that most research money in Greece comes from the public purse, the current fiscal constraints mean it is impossible to boost spending to more than 1% of GDP. This means that the only way to grow R&D spending is for the private sector to step in and invest in highly selected R&D projects that have serious possibility to lead to high added-value exportable products and/or services and thus ignite the real economy. There have been a couple of instances where this has happened – BIC (disposable pens, razors) expanded its global research centre near Athens, and a few Greek pharmas have intensified generic drug development – but mostly this seems unlikely.

For us who are serving the small and fragmented biotech sector in Greece, the crisis may turn out to be an opportunity. However, there are interesting questions to consider: Will there be a renaissance of the biotech/pharma sector after the crisis, or are we getting closer to a definitive government decision that this sector is unlikely to be one of the key areas for development? What are the elements needed to boost the commercialization efforts of Greek bioresearch? What role can Greek universities and research centers play? Greek pharma companies currently heavily invest in generics; is this a real opportunity for Greece? How can the Greek-American bioentrepreneurs get involved in the process?

Although we often ask ourselves questions like these, hoping to find information that would enable us to more effectively lobby for biotech funding, there is not always comprehensive data from which to draw conclusions.

I’m currently strategic advisor to Genomedica, primary tasked with establishing critical R&D biopartners in personalized medicine. I’ve been working in the biomedical and innovation field for more than twenty years. With Athina Ikonomidou, a business development and technology transfer consultant specializing in biotechnology, we plan to write about the advantages Greek biotech has, as well as its obstacles, and to investigate these questions.  More to come.

Iordanis Arzimanoglou