World Hepatitis Day 2011

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Today, 28 July 2011, marks the first World Hepatitis Day that is officially supported by the World Health Organization.

While the disease claims around one million lives every year, and millions more suffer long-term illness and severe complications, its burden is no more evident than in Egypt, where Hepatitis C is a serious epidemic.

Here are some numbers to put the scope of the epidemic in focus:

1) While globally, roughly one in every 50 people is infected with Hepatitis C virus, that rises to one in every seven of people living in Egypt. That means a little over 14% of the most populous Arab state have been infected with the virus at some stage of their lives.

2) A total of 10% of the population are, however, carrying the viral load and are thus chronically infected. This is by far the largest percentage in the world. In fact, it is over five times higher than other countries that have high Hepatitis C rates.

3) A recent 2010 epidemiological study has suggested that more than half a million people get infected annually with Hepatitis C in Egypt.

4) 40,000 people die annually in Egypt due to Hepatitis complications, such as liver failures and cancers. Hepatitis C is the second biggest cause of death following heart diseases.

5) Around 75% of all cases of liver cirrhosis and liver cancer in Egypt and the Middle East are caused by Hepatitis infections.

6) So far, there are no vaccine for Hepatitis C. There is no effective treatment either, the current 48-week treatment course of interferon and the antiviral drug ribavirin is expensive and has a success rate of around 60%.

But all is not gloomy for Hepatitis C. A recent Nature Outlook on Hepatitis C, has looked into the challenges the disease poses, but also takes a look at several new drugs about to be launched that could substantially improve treatment.

The greatest challenge to combat the virus will remain, however, raising awareness. While Hepatitis C is mainly spread through healthcare services since it is a blood-borne virus, bad social practices help spread it as well. This includes reusing razors at barber shops and using repeatedly using the same equipment for circumcision of boys in poorer areas of the Middle East.

I’m hopeful that events such as the World Hepatitis Day do help raise awareness and empower people to inquire, especially when visiting healthcare practitioners, about the measures they took to protect their patients from Hepatitis C.

Summer science camp for disadvantaged young girls

Yara Sifri, a Palestinian-Canadian 17-year-old Massachusetts high school student, has raised nearly US$30,000 to create a science camp for disadvantaged young girls living in refugee camps in Amman, Jordan.

Sifri explains that SciGirls, the two-week summer science camp she created, was born out of her “passion for science.”

Mohammed Amin refugee camp is an unofficial camp in the Jabal Al-Natheef district in Jordan, so living conditions there can be dismal. Education opportunities can be rare, and once they arise they are usually given to boys rather than girls.

According to a UNESCO 2010 report, female scientists in Jordan make up 21% of the science community, much lower than the Arab world average of 35%

“I wanted to bring to these girls some of the opportunities I had in Montreal,” Sifri told <a href=” https://articles.cnn.com/2011-07-12/world/scigirls.jordan_1_science-camp-robotics-team-local-teenage-girls?_s=PM:WORLD “>CNN World.

Sifri’s summer science camp was possible with help from Ruwwad, a local NGO, which convinced parents in the conservative region to allow their daughters to go to the camp.

A total of 44 girls with the highest grades in science in school were selected for the camp. They are bussed back and forth each day during the two-week programme to the Jubilee Center for Excellence in Education, which is located in another part of Jordan.

“The girls will learn about robotics, they’ll do basic circuits and learn about solar panels and electricity. There is also a maths and chess component,” said Sifri.

The girls will also enjoy activities such as playing football and mural painting in-between.

While this is the first year SciGirls is held, Sifri plans to make it an annual event during the summer, when she travels to spend her school vacation with her grandparents in Amman.

“The girls will learn about robotics, they’ll do basic circuits and learn about solar panels and electricity. There is also a maths and chess component.”

Below you can watch a short video that Sifri and Ruwwad have prepared from the SciGirls camp.

First gene bank in the Arab world to open in Qatar

In a joint project between Qatar Foundation, Hamad Medical Corporation, Qatar, and the Imperial College of London, Qatar announced its plans to launch and host the first gene bank in the Arab world.

The project, named Biobank Qatar, is scheduled to open its doors within a year to collect blood or tissue samples from volunteer donors. These will be used for research for common diseases in Qatar, such as diabetes and heart diseases.

The new gene bank aims to collect 20,000 samples from Qatari and Arab volunteers within the first 10 years. The research could lead to the development of new drugs that may be more efficient for this group in particular. It can also help in the development of the Arab genome further.

According to the Qatari daily newspaper The Peninsula, the team behind Biobank are taking issues of genetic privacy seriously, ensuring consent on behalf of the donors and putting in place a system to withdraw samples at any time if they so decide.

“We will focus on taking detailed pictures of diseases in the Arab community, taking into consideration that the genes of Arab citizens differ from the genes of Westerners,” said Hanan al-Kuwari, board chairman of the bank and the director of Hamad Medical Corporation.

According to a 1999 survey, 15% of Qataris have diabetes and an additional 11% have impaired glucose tolerance. Diabetes treatment alone accounts for 10% of Qatar’s huge healthcare expenditure.

Genetic research is an important field to focus on to usher in an age of personalized medicine, Fathy Saoud, president of Qatar Foundation, told the website Al-Shorfa. Collecting genetic data from the community will “allow researchers to tackle diseases on an individual basis, and not just predict the diseases,” he added.

The Somalia famine – A 21st century disgrace

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Last week, the UN finally declared a famine in large areas of southern Somalia. Hundreds of thousands of Somalis in the region are at risk of dying if aid does not arrive soon.

This is the first famine the world has seen since 1991 (which was also in Somalia). Now, 20 years later, and after all the technological advantages we have made, humanity seems to stand at the door of another famine.

The area where the famine was declared has been suffering one of the worst droughts since the early 1950’s, according to the aid group Oxfam. While the drought is the main driver behind the famine, the volatile political situation in Somalia is also worsening the situation.

Several years ago, Islamist militant groups who wrangled control of the south of Somalia kicked out all Western aid agencies. Today they are downplaying the seriousness of the famine but have allowed aid to trickle in.

According to the UN, a famine is declared when three conditions are met:

1) Over 20% of the residents in an area live on less than 2100 kilocalories per day

2) At least two people per 10,000 people or four children per 10,000 children

3) An acute malnutrition that affects more than 30% of children in the affected area

The situation has reached critical status now in Somalia, and observers are worried the famine might soon spread to other parts of the country amidst the lack of a central government to handle the issue effectively.

The problem is that these issues do not wait for politics. Aid groups have pointed fingers at Western governments who have dragged their feet in addressing the famine, even though the UN has been raising danger flags since January this year.

However, my question is why have the governments of the rich Arab states and Muslim-majority states not done anything? The Islamist militants ruling south Somalia right now are wary of the involvement of aid groups from the West, but surely they would have been open to receiving aid from those states they share an ethnic link with.

I think the finger pointing should be directed at these states as much as the West. They have the funds and they have allocated much to aid over the years, but maybe they should be looking closer to home to save those people suffering from a famine, a condition I find is a disgrace to humanity in the 21st century.

Granted, the Kuwaiti Red Crescent sent the first aid shipment to Somalia after the UN declared the famine, which is a very positive development, but there is still much that needs to be done.

Zahi Hawass out (yet again!)

zahi hawass.jpgIf there is one person I blame for ruining a childhood hero, it would be Egyptian antiquities minister Zahi Hawass. He completely ruined Indiana Jones for me when he adopted his symbolic hat.

Hawass was, finally, fired from the intern cabinet and will be replaced tomorrow – to the relief of thousands of archaeologists protesting against him – during a large cabinet reshuffle.

The Egyptologist Hawass, with his larger-than-life attitude, quickly became the face of ancient Egypt by appearing on countless international programmes, most prominently on National Geographic, talking about the ancient civilizations that lived here thousands of years ago.

Hawass has often been accused by fellow archaeologists of stifling debate and attributing scientific findings to himself even when not involved. There has been several protests against him by archaeology graduates since ousted President Mubarak’s regime collapsed.

Though Hawass resigned from his post after the revolution toppled the Mubarak-appointed government he was part of, he was reappointed as antiquities minister less than a month later.

The Egyptian daily Al-Youm Al-Saba’a reported that Hawass had to leave the ministry building from the back door, after being chased by archaeology graduates protesting at the front gate of the minister asking for his removal from his position.

However, following prime minister Essam Sharaf announcement of Hawass’ successor, Abdel Fatah El-Banna, an associate professor in restoration, archaeologists across the country mounted a huge campaign against the move. They threatened mass resignations and closing down of archaeology sites across Egypt if the decision goes through.

This prompted a delay in the announcement of the new cabinet, as El-Banna declined the post and the prime minister went back to discussions to choose a new replacement for Hawass.

Till then, however, protesters in the iconic Tahrir Square, the epicentre of the Egyptian revolution, celebrated what they hope is Hawass’ final departure.

Schistosomiasis is over 1,500 years old

Schistosomiasis, a parasitic disease that used to be the leading cause of liver cirrhosis in Egypt before being superseded by hepatitis C, has been plaguing Nile-dwellers for a long long time, according to evidence from recently discovered mummies.

Schistosomiasis, also known as bilharziasis, is caused by an infectious worm that lives part of its lifecycle within freshwater snails. These snails prefer stagnant water and are quickly washed away in flowing water. That is why bilharziasis is much more prominent in irrigation canals, which are a perfect habitat for the snail hosts before they infect humans through their skins.

According to ScienceOnline, anthropologists analyzed tissues from two sets of Nubian mummies excavated at the border between Egypt and Sudan. One group used the flowing and flooding waters of the Nile to irrigate their land while the other one dug canals and relied on artificial irrigation to grow their crops.

The mummies from the community that dug these canals were found to have 25% higher parasitic load than the group that irrigated off the Nile waters directly. This reflects a pattern that is similar to the same situation of many Nile-dwelling farmers in Africa now.

Schistosomiasis started to rapidly spread in North Africa in the 1950’s following the construction of large dams and irrigation projects to feed growing populations and to increase fertile lands. The rapid rise of infections with the worm causing the disease can be correlated to the spread of these projects.

Where science in the Arab world went wrong

Cairo University

In the 1960’s and 1970’s, many Arab states, fresh out of stifling colonial occupations, turned to the West to try to jumpstart science and education in their societies. The ambitious programmes were quite successfully, until they slowly started to wane.

During these years, thousands would travel to Europe (mainly the UK and France) on scholarships, mostly sponsored by their local governments, to study the latest biological, physical and social sciences, and bring them back. These professors were then given positions in the fledgling Arab universities to ‘transfer’ what they learned to more people.

At the same time, professors from the best universities overseas were invited to spend some time in these Arab universities. It was normal practice to see foreign professors in these universities, mingling and working with their Arab counterparts, while teaching students from a very different culture.

Thus these universities truly became centres of enlightenment in the region. They were held in high regard and respect by everyone and the faculty and students themselves carried this enlightenment beyond the universities walls to the average person on the street.

Then, starting from the mid-80’s, the number of scholarships started to decrease sharply. The governments just weren’t as interested as before in sending people abroad for their post-graduate studies. Their argument was that “we have already received the science we need from the West, we don’t need to send people there now.”

By that time, there were several post-graduate programmes in the region and more opportunities for university graduates to continue learning locally rather than travelling abroad. Consequently, the number of visiting professors dropped drastically (because the governments saw they didn’t need them anymore and they cost too much). It is now very rare to see a non-Arab professor in a public university in one of the Arab states.

The universities were getting crowded, the quality of education was dropping, and that beacon of enlightenment started to wane.

The problem is that the governments got it all wrong (at least so in my opinion). The universities weren’t flourishing because they needed Western science at that period, they were flourishing from the interactions between the Western professors and their Arab counterparts. They flourished because, by it’s very nature, science was becoming an international, cross-border affair.

More important than the science that was coming from the West was fermenting a science culture in the Arab world after decades of marginalizing science in the past.

The Arab world is slowly realizing this, which is why the richer Gulf States in particular have started to collaborate with international institutes to promote science and research. By becoming part of the international science community, rather than isolating itself, they stand their best shot at realizing their dream of becoming knowledge-based societies.

These international collaborative issues do not need to focus on the developed world only. The developing world is just as important a partner, as it faces similar problems like the rest of the Arab world and thus the collaborations would be more meaningful for both parties.

And, as a bonus side effect, these collaborations give the best shot ever at bridging an ever-expanding misunderstanding between the West and the Arab world. Science is one universal language that has done more for diplomacy and promoting understanding than most other efforts exerted by the West so far!

Maybe its time for the West to give science diplomacy a real shot rather than half-hearted efforts.

You lucky horses! (or are you?)

During our trip to Doha, Qatar, for the WCSJ2011, we were introduced to some 168 horses living a luxurious life, far better than roughly 95% of humans across the globe, but there is a catch – a very serious catch.

The Arabian and Egyptian pure-blood horse breeds that are being bred in the Shafaq Horse Stables belong to the Emir of Qatar. The horses, which can often run for tens of millions of US dollars in value, live and sleep in air-conditioned stables away from the scorching 45°C+ of summers of Doha, Qatar. They have a swimming pool to cool off, special treadmills to workout twice a week, and saunas and special oils that are rubbed on them regularly to smooth their muscles in cases of cramps and so.

Sounds too perfect to be true? This is where the catch comes in. All breeding is through artificial insemination. According to our guide in our trip around the stables, the stallions have never had “the real thing.” We passed through a room containing what is called artificial vaginas, which are used to collect the sperms and then use them to impregnate an egg from a mare before it is reinserted to grow within the mare’s womb.

They take it even one step further. If a mare has especially good and desirable genes, then they would take several eggs and impregnate them with sperms (from a stallion with perfect genes too) and use surrogate mothers (who’s genes may not be that perfect) in order to breed more horses.

That is how far they would go to breed genes that produce perfectly formed horses. Note these horses are not bred for speed, but for form and beauty. they compete in beauty contests for the perfect body (with very stringent standards at that!)

Now what I found particularly interesting (and worrying) is that the breeders are basically breeding out any genetic diversity or evolution. There are variations brought forward – the horses are almost identical genetically on and on. As pretty as the horses are, I can’t help but wonder what if they are susceptible to one mutated bacteria or virus? That could wipe out the entire bloodline due to the lack of any variations.

According to our guide, they don’t worry about that now because the horses are already getting extremely high quality health benefits. However, they have started sending some breeds out to different continents to spread them out.

“Maybe in possible smaller countries, they might have to rely more on nature a little more,” she adds. “The horses are completely vaccinated and they will go through six months of quarantine, but it will be interesting to see what kind of immunities they will build up for something in South America for example that we don’t have here in Arabia.”

I just hope it is not too late to build up those immunities after wiping out any sort of genetic variations in the bloodlines. For now, you can enjoy the pictures here of the extremely beautiful horses being bred in stables that would be the envy of humans, let alone other horses!

Egyptian professor wins prestigious award

azzazy_bg.jpgThe Academy of Scientific Research and Technology in Egypt has awarded the National Excellence Prize in Advanced Technological Sciences to Hassan Azzazy, chemist and associate dean for graduate studies at the American University in Cairo (AUC).

The award recognizes science outreach efforts of the scientist as well as their publications and their impacts. Azzazy has published 16 articles in international peer-reviewed journals over the past 5 years.

“The timing of the award is also special as it comes in the post-revolution era where scientific research has been declared as a national priority. I am also pleased because this award recognizes the efforts of the bright graduate students in my research group,” said Azzazy in a press release announcing the award.

Azzazy and his team have previously pioneered a new method for the rapid detection of Hepatitis C RNA in the bloodstream using gold nanoparticles. Hepatitis C is the largest healthcare burden in Egypt, infecting some 14% of the population there.

Through a significant fund from the Qatar National Research Foundation (QNRF), Azzazy is developing and optimizing a more advanced form of the technique which will be used to diagnose hepatitis C and tuberculosis.

Egypt’s interim government has announced a renewed focus on scientific research, boosting research spending to 0.3% of GDP this year with an overly ambitious vision to reach 2% within five years.

Speaking on a panel on the future of science in post-revolution Egypt at the World Conference of Science Journalists, Azzazy criticized the minimal role that science has played in Egypt for the past few decades, citing few examples of true scientific progress under Mubarak’s regime.

“We need to have something big, especially in research. We do not have any actual scientific research in the public universities in Egypt. If you visit any of them and see the number of research papers published in international peer-reviewed journals it’ll be zero,” said Azzazy.

“Scientific research in Egypt needs a boost because, right now it is in a very position.”

Besides the work on the gold nanoparticle detection technique, Azzazy and his team are also developing smart drug nanocarriers to treat tuberculosis and researching new drugs that may prevent the hepatitis C virus from entering liver cells.