Tag Archives: children

Beating cancer with smarter use of radiation?

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This is a guest post by Nature Middle East writer Hebah Salama.

Cancers infect different tissues, and so they manifest differently, in various types, and require different treatments or sometimes a combination of treatments. Throw in variability among patients as a factor, and it’s even more complicated. It’s the reason why numerous studies are carried out every year to try and gauge the most effective therapy for different cancer types.

Now, researchers from Sudan and Lebanon specializing in medical physics and biochemistry have collaborated together on one such study. Their research deals with cancer cases in children, specifically analyzing the effect of different single radiation doses of X-rays on Rhabdomyosarcoma (RMS) – a malignant tumor involving skeletal muscle tissue.

Radiation, one of the most commonly used methods of cancer treatment, is known to cause damage in both healthy and cancerous tissue. It’s what sparked the known risk-benefit-ratio debate on whether the benefits from radiation therapy outweigh the harms. Scientists often discuss the different methods in which radiation can be used while keeping its side-effects to a minimum. As well, new technologies that provide high accuracy in dose delivery have been invented for this purpose; sparing healthy cells.

In this study, the scientists treated cultured RMS cells in vitro (outside of the human body) with therapeutic X-rays. The cells have shown to be resistant to radiation. Additionally, and depending on the radiation dosages, many of the treated cells have repaired from the X-rays’ radiation damage.

The scientists use this study to demonstrate that efforts put into studying tumors’ and healthy tissues’ biological responses to radiation based on tumor type should be stepped up. The more accurate the data provided about these types of responses, the better the outcome of patient treatment is.

“The advancement in technology should be met with more scientific research,” says Alexander Fadul lead researcher.

He adds that more patient oriented studies are certainly needed to determine the different parameters of radiation.

Roman Egypt was home to “a good citizenship” youth organisation 2,000 years ago

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Ancient Egypt GOODSHOOT

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Following a study of over 7,500 ancient documents on papyrus, originating from Oxyrhynchos in Egypt and discovered over a hundred years back in a rubbish dump, University of Oslo and the University of Newcastle presented what is perhaps the most systematic research of childhood in Roman Egypt, according to the university’s website.

Among their discoveries? Some 2,000 years ago, Oxyrhynchos, a town of around 25,000 inhabitants, had a youth organisation, called a “gymnasium,” in which any free-born child could enroll – slaves and girls not allowed.

Somewhere between 10 and 25% of local Egyptian boys, in addition to Greek and Roman residents of Egypt would have qualified, but typically members of affluent families and higher tax classes enrolled, according to an overview of the study released earlier this month by social historian Ville Vuolanto of the University of Oslo and April Pudsey of the University of Newcastle.

Enrollment in the gymnasium marked the transition to adulthood.

“It’s like putting together a jigsaw puzzle. By examining papyri, pottery fragments with writing on, toys and other objects, we are trying to form a picture of how children lived in Roman Egypt,” explains Vuolanto.

While well-off boys were part of the prestigious gymnasium, learning to be good citizens, others worked or landed what is termed “apprenticeship contracts,” mainly in the weaving industry. Either way, boys in ancient Egypt were not considered fully adult until they got married, usually in their early twenties. Most girls remained or worked at home, according to the study.

Slave children could also become apprentices, however, unlike “free-born” citizens they lived with their owners or “masters” not their parents during. Vuolanto says that children as young as two were separated from kin and sold as slaves.

“Little is known about the lives of children until they turn up in official documents, which is usually not before they are in their early teens,” says University of Oslo’s press release.