Year in review: Under pressure

Conflict and wars have continued to bend the region out of shape in 2016, with health infrastructure in Syria and Yemen continuing to crumble and fall, and the exodus of people out of dangerous zones affecting neighboring populations. The following are some of the most critical situations borne out of the flow of people as a result of infighting in 2016.

Water

Besides the human cost of the war in Syria, the ecological and environmental impact has, no doubt, been huge. For example, earlier this month, researchers based in the US and Canada have shown how mass migrations are changing the country’s hydrological landscape.

The flight of Syrian refugees since 2013 has dramatically changed water-use patterns and led to an increased water flow into Jordan through the Yarmouk River. In the absence of direct measurement data from Syria, the scientists had turned to remote sensing techniques, combining spatial and statistical analyses of satellite imagery with water balance calculations to estimate the changes in irrigation patterns and reservoir usage in southwest Syria. While the end of a regional drought is partly responsible for the increased flow of the Yarmouk, the analysis showed that decreased water use in the Syrian part of the river basin accounts for roughly half of the 340% increase in transboundary flow.

In a way, the war in Syria carried some good for Jordan – at least in terms of water supply.

Health

War and migration had once led to outbreaks of infectious diseases, such as visceral leishmaniasis, across the region, originating from Sudan and South Sudan. And new research is warning that this could happen again. Visceral leishmaniasis is endemic in Sudan and South Sudan, where the climate allows sandflies to thrive, and poor health systems compound the problem.

Researchers from the US and Saudi Arabia have presented new evidence suggesting that conflict, and the chronic malnutrition and displacement that follow, interrupt the cycle of immunity and allow a disease like visceral leishmaniasis to flourish. Gloomily, the scientists say they expect another outbreak.

Not far off, in Aleppo, the scene of much violence and suffering, an outbreak of another form of leishmaniasis has taken place. The Aleppo boil, which is caused by a parasite in the bloodstream and transmitted through the bites of sandflies, has been reported to have infected hundreds of thousands across the Middle East, especially across refugee camps. The disease causes disfiguring lesions on the body and the numbers are bad, according to scientists.

Until recently, the disease was contained to areas around Aleppo and Damascus, but this changed with the continuous disruption of insecticide control, poor water and sanitation services in conflict zones.

Beating cancer with smarter use of radiation?

This is a guest post by Nature Middle East writer Hebah Salama.

Cancers infect different tissues, and so they manifest differently, in various types, and require different treatments or sometimes a combination of treatments. Throw in variability among patients as a factor, and it’s even more complicated. It’s the reason why numerous studies are carried out every year to try and gauge the most effective therapy for different cancer types.

Now, researchers from Sudan and Lebanon specializing in medical physics and biochemistry have collaborated together on one such study. Their research deals with cancer cases in children, specifically analyzing the effect of different single radiation doses of X-rays on Rhabdomyosarcoma (RMS) – a malignant tumor involving skeletal muscle tissue.

Radiation, one of the most commonly used methods of cancer treatment, is known to cause damage in both healthy and cancerous tissue. It’s what sparked the known risk-benefit-ratio debate on whether the benefits from radiation therapy outweigh the harms. Scientists often discuss the different methods in which radiation can be used while keeping its side-effects to a minimum. As well, new technologies that provide high accuracy in dose delivery have been invented for this purpose; sparing healthy cells.

In this study, the scientists treated cultured RMS cells in vitro (outside of the human body) with therapeutic X-rays. The cells have shown to be resistant to radiation. Additionally, and depending on the radiation dosages, many of the treated cells have repaired from the X-rays’ radiation damage.

The scientists use this study to demonstrate that efforts put into studying tumors’ and healthy tissues’ biological responses to radiation based on tumor type should be stepped up. The more accurate the data provided about these types of responses, the better the outcome of patient treatment is.

“The advancement in technology should be met with more scientific research,” says Alexander Fadul lead researcher.

He adds that more patient oriented studies are certainly needed to determine the different parameters of radiation.