A great question

[This post is based on the editorial in the March 2011 issue — the full text can be accessed here, available for free to all registered users. We welcome feedback on our editorials in the comments section below.]

Who is the greatest chemist of all time?

These eight simple words pose a question that is far from simple to answer. The first obvious problem is with the concept of ‘greatness’ — how should this be defined and measured? Secondly, would everyone agree with exactly what is meant by the term ‘chemist’? There are some prominent historical figures that both chemists and physicists would claim as their own.

Another complication is a fundamental (and unavoidable) one associated with all questions and polls of this type — the influence of time. Consider the world of sport for example — when a team or an individual becomes very successful, comparisons are often made with so-called ‘greats’ of a bygone era. But in the same way as it would be impossible for the Manchester United teams of 1968 and 1999 to play one another to inform a fair comparison, how do we judge the relative merits of the contributions that Wöhler and Woodward made to chemistry?

In spite of these problems, there is undoubtedly some value in asking (and responding to) questions of this kind. Yes, the answers will be subjective, but it’s the debate surrounding the answers — and indeed the question itself — that often prove more interesting than the final results or ranking. We asked the greatest-chemist question on our journal’s Twitter feed back in early January and gave a comprehensive round-up of the responses we received on this blog.

To our surprise, there were some truly great chemists missing from the list. No Gibbs, no Dalton and no Priestley. One omission in particular, that of the only person to be awarded two Nobel Prizes in Chemistry, sparked some debate in the blogosphere at the Curious Wavefunction and Second Messenger. Was Sanger’s name missing because chemists tend to focus on fundamental topics such as structure and bonding rather than more applied aspects? And, as discussed at There (& Hopefully) Back Again, should our evaluations of the ‘greatness’ of a scientist change when we consider not just their momentous achievements, but also their more nefarious (Haber) and/or eccentric (Pauling) pursuits? The greatest-chemist debate continued on a number of other blogs including ChemBark, and ScienceGeist and we encourage you to read them and their comment threads to get a feeling for what others think.

The main point of asking the question was not to uncover a definitive answer as to who the greatest chemist of all time is, but to see if any consensus did emerge and how many different suggestions were put forward. Whereas in physics it is hard to see past Einstein leading the way in this sort of exercise, we were curious as to whether a similar figure would emerge for chemistry.

Would any of us have picked Pauling (the eventual ‘number 1’) to lead the chemistry one with the same certainty? Of course, Einstein and the photos of him with stereotypical ‘mad-genius’ hair have crossed into popular culture — and this is certainly not the case with Pauling. Is the lack of a recognisable figurehead in chemistry a problem? Perhaps a greater awareness of some of the inspirational chemists of the past would help spark the imagination of budding chemists out there today.

Our Twitter poll, as we suggested at the time, was somewhat arbitrary and unscientific — as is the question itself. Nonetheless, it is clear that, even from such a small data set, many different individuals are considered to be greatest chemist of all time. They can’t all be the greatest, but that matters not — they are all great, and this reflects the strength and diversity of chemistry.

Why scientists should blog about their pets

Our March issue went live today, featuring a Thesis article (sub req’d) from Michelle Francl about blogging – here’s a little extra from Michelle that expands on her column.


Last fall, Royce Murray stirred up science bloggers by characterizing them as unqualified purveyors of pseudoscience in search of easy money. The response was fast and furious – so robust in fact that performing the Google search that Murray referred to in his argument “qualifications of bloggers” now turns up as many hits to science blogs responding to Murray’s editorial as it does adverts and advice for the unqualified seeking to blog (at least in the top twenty!).

I argue in my Thesis column this month that chemistry blogs are a critical part of the communication network which supports good research – and that scientists should read, and if they are so inclined write, blogs of this sort.

What I didn’t say is that I would extend this to suggest that scientists should be doing more than utilitarian writing. We should move beyond the writing of journal articles, reviews, abstracts, and even blog posts critically commenting on the literature and write about the quotidian challenges of doing science, extol the beauty of our latest compound, wax philosophical about the reality of molecular orbitals, and dare I say it, blog about our pets.

Simply writing more is a strategy to become a faster, fluent and more efficient writer. Why not write summaries of the latest literature? Why do I think writing about the steamboat buffet my student treated me to in Singapore or my cat’s latest predatory exploits is worth my time? Because I can write with the brakes off. I can use language wildly, without worrying about transgressing technical boundaries or overreaching my data.

Learning to deploy rich descriptive language takes practice, and has hidden benefits to the research scientist. Scientists’ field notes and lab notebooks would benefit from fluent, descriptive writing – and so, in my experience, would the science that flows from them. The original sceptical chemist, Robert Boyle, held that science wasn’t officially science unless you’d watched the experiment happen yourself – or read something written so evocatively and carefully that you could think you’d seen it.

So, go for it. Write down everything you know about Jello, or a time you itched or the stupidest thing your dog did last week. Write over the top and outside the bounds for five minutes a day. Post it on your blog or stuff it down the oubliette. Either way, your science will be all the better for it.

‘Top chemists’ continued

Since we published our previous post, Wavefunction has also written about the list, asking ‘Is the age of traditional organic synthesis over?’ He noticed that there are fewer organic chemists on the list than you might think, and certainly fewer than he’d expect from “any such list from the 50s through the 90s”, which “would have been dominated by organic chemists engaged in methodology and total synthesis”.

Would it? Michelle Francl managed to dig out a list of “”https://www.ccp14.ac.uk/ccp/web-mirrors/armel/www.cristal.org/1000chimistes.html">ISI’s 1000 Most Cited Chemists, 1981-June 1997".

Throwing the data through my trusty spreadsheet, I removed those with <50 papers in that period (as the latest THE table did) and ordered by average citations per paper to get this top 10:

BAX,A; 142.47

SMALLEY, RE; 108.92

CURL, RF; 95.2

BRUS, LE; 85.96

DEWAR, MJS; 81.52

HEHRE, WJ; 81.32

POPLE, JA; 79.8

ERNST, RR; 71.81

NUZZO, RG; 70.77

GROVES, JT; 69.37

I don’t really think any of those count as synthetic organic chemists. Looking at the list ordered by total citations doesn’t change that too much either (for what it’s worth the top 10 is: BAX, POPLE, SCHLEYER, ERNST, WHITESIDES, SCHAEFER, HUFFMAN, RHEINGOLD, SEEBACH, LEHN).

So, was there ever a “golden age of organic synthesis” where chemistry as a whole was dominated by the big beasts of synthesis? Or – to be fairly provocative – are organic chemists just a little insular and think that their bit of the chemistry kingdom is the only one that matters?

Neil (a solid-state inorganic chemist!)

Neil Withers (Associate Editor, Nature Chemistry)

‘Top chemists’ 2000-2010

Just when we thought we could breathe easily without trying to rank how great people are, we find that The Times Higher Education has a story out today that features some ISI/Thomson Reuters data on who the ‘highest impact’ chemists were from 2000-2010.

Feel free to read neither this post nor the THE article and go straight to the table in this PDF.

The data given is all from ISI/Web of Science: papers published, citations and ‘impact’ (citations per paper). I’ll give you the top ten here:

Charles M. LIEBER; Harvard University (74 papers, 17,776 citations, 240.22 c/p)

Omar M. YAGHI; University of California Los Angeles (90, 19,870, 220.78)

Michael O’KEEFFE; Arizona State University (73, 12,910, 176.85)

K. Barry SHARPLESS; Scripps Research Institute (60, 9,754, 162.57)

A. Paul ALIVISATOS; University of California Berkeley (93, 14,589, 156.87)

Richard E. SMALLEY†; Formerly Rice University (60, 9,217, 153.62)

Hongjie DAI; Stanford University (88, 12,768, 145.09)

Xiaogang PENG; University of Arkansas (59, 8,548, 144.88)

Valery V. FOKIN; Scripps Research Institute (54, 6,853, 126.91)

Peidong YANG; University of California Berkeley (95, 11,167, 117.55)

We do have a note of caution, however: we’ve tried to reproduce the results ourselves in Web of Science, but can never get quite the same numbers out. Maybe our WoS skills aren’t quite up to those of the analyst who produced them.

Anyway, it’s moderately interesting to see this and note a few points of interest (Richard Smalley’s doing well, all things considered; no Stoddart?) but I’m not sure if it tells us anything earth-shattering.

The ISI release was spinning something along the lines of a nano-takeover (“60 out of the top 100 chemists identifying nanotechnology as either their main focus or a significant research topic”), while the THE article gives the RSC a bit of a soapbox (“[RSC chief exec] warned the EPSRC against squeezing out blue-skies research”).

I’ll leave it to you guys to have a good look and tell us what trends/datapoints you find interesting.

Neil

Neil Withers

(Associate Editor, Nature Chemistry)

IYC2011 Global challenges webcast

Today, the Chemical Heritage Foundation in Philadelphia launches the International Year of Chemistry in the USA with a debate on the “solutions to the pressing issues of energy, water, food, and human health”.

If you didn’t register in time, fear not – the discussion is being webcast between 10am and noon (EST). With the following list of participants (CEOs of Dupont AND Dow?!), it really looks worth tuning in to:

Daniel G. Nocera (moderator), Henry Dreyfus Professor of Energy and Professor of Chemistry, Massachusetts Institute of Technology

Joshua S. Boger, former Chair and CEO, current Board Member, Vertex Pharmaceuticals

Rita Colwell, Distinguished University Professor, University of Maryland at College Park, and former Director, National Science Foundation

Janet Hering, Director, Swiss Federal Institute of Aquatic Science and Technology

Ellen Kullman, Chair and CEO, DuPont

Andrew N. Liveris, President, Chair, and CEO, The Dow Chemical Company

You need to register in advance at this webpage, then you can log in to the webcast from 9.45am.

Neil

Neil Withers (Associate Editor, Nature Chemistry)