Chemical showers

Best house-warming gift.

Ever.

Period.

Well, periodic, really…

Along with the fantastic wine, flowers and chocolates, we now have a fabulous periodic table shower curtain (Thanks Tom)! OK, we’ve all seen periodic table mugs and T-shirts, but a shower curtain of the elements – I didn’t know such things existed…

What other periodic table paraphernalia have you come across – and can anybody beat a shower curtain!?

Stuart

Stuart Cantrill (Senior Editor, Nature Nanotechnology)

Chemical communications

As you may have noticed (and some of you have commented on), The Sceptical Chymist has recruited a range of guest bloggers. Although NPG editors will continue to contribute, we wanted to add some new voices that can offer different perspectives on chemistry and describe their experiences from within (or beyond) the chemistry community. The team is as follows:

Materials Girl: In her own words, ‘a wide-eyed undergraduate student who rambles on about anything university and [ultimately] chemistry-related that strikes her fancy’.

Sugar Daddy: A fourth year graduate student working in a chemical biology lab doing research that involves a ‘little bit of synthesis, little bit of biology’.

Prospective Professor: A postdoc on the hunt for an academic position.

Rookie Rocky: Hubert is a brand new assistant professor facing up to the challenges of the job, including what it means to sit in the front row at seminars!

10 Miles from Academia: Jeff Johannes – a medicinal chemist at a major pharmaceutical company in the Boston area – offers us a different perspective on breakthroughs in chemistry.

Confessions of a former chemist: Even further away from academia, Mushy is a PhD-chemist who left it all behind to go and work in IT in the City of London, but still has a soft spot for all things chemistry.

So, there you go, an undergrad, a grad, a postdoc, an assistant prof, an industrial chemist and an ex-chemist – we hope you enjoy reading.

Stuart

Stuart Cantrill (Senior Editor, Nature Nanotechnology)

Materials Girl: Synthetic limericks

Posted on behalf of Materials Girl

These are ‘stolen’ from a good friend of mine who proves that chemists can be witty, too! My Facebook page – yes, that infernal, horrendous, time-wasting network – is well-stocked with his quotes. The second limerick is probably the best I’ve ever read.

There once was a fellow from Stowles

Who bred cockroaches, rabbits, and voles

Asked how he could keep track

Of this prolific pack

He replied “I just count them in moles.”

A Chemist, gone mad with distraction

Hurled into the sea his reaction.

To atone for this loss

He was made by his boss

To recover it via extraction.

Can anyone out there do any better?

[Editor’s note: first it was haiku… now limericks, what next?!!]

Reactions – Simon Webb

1. What made you want to be a chemist?

I actually wanted to be a scientist from a young age, and had early flirtations with zoology and physics. However, my father was responsible for my conversion to chemistry; he bought me some books on chemistry and a big bag of sulfur, then turned a blind eye to the resulting noxious vapours that emerged from the tool shed.

2. If you weren’t a chemist and could do any other job, what would it be – and why?

I guess there are two other areas that interest me. I love reading, so owning a bookshop has always been an attractive idea. I’ve also found the ins and outs of running a small business fascinating (my father’s influence again).

3. How can chemists best contribute to the world at large?

I’m sure chemistry’s best contribution will come from an unexpected area, so diversity in research is essential. However, I think improving human health and lifespan will continue to be a primary concern for society. The rapid increase in our knowledge of cellular chemistry offers great opportunities for chemists in this area, and there will be a need to create new classes of highly specific drugs and biomaterials for an aging society. Finally, improving public understanding and perceptions of science is a great challenge for all scientists, including chemists.

4. Which historical figure would you most like to have dinner with – and why?

I’ve become interested in the life of Ernest Rutherford since recently discovering that he used to live close by in south Manchester. I would like to know how he felt about his transition from resident of small town New Zealand to one of the great researchers of the modern age.

5. When was the last time you did an experiment in the lab – and what was it?

Unfortunately I don’t have the opportunity to work in the lab very often; it is certainly something I miss. My last experiment was about 3 months ago, testing an experimental procedure that I’d suggested for a schools’ liaison event. Pushing my diminishing experimental skills to the limit, I produced several grams of copper carbonate.

6. If exiled on a desert island, what one book and one CD would you take with you?

I’d take a nice thick history book, probably on Ancient Rome (a current passion), along with “Discofreakout”, a compilation of 70s’ disco hits. After finishing the book, I would burn it to attract passing ships.

Simon Webb is in the Department of Chemistry at the University of Manchester, UK, and uses chemistry to mimic aspects of biological systems, particularly the structure and function of biological membranes.

Chemistry for chemistry’s sake

In case you’ve been lax in your chemistry-doing this week – get to it! It’s National Chemistry Week, after all!

The theme for this year is ‘the many faces of chemistry,’ which seems to actually refer to the many different careers that chemists have. People often think that being an editor is a pretty unusual job for a chemist, but at least we still spend our time thinking about science even if we’re not doing actual experiments. Surely there are more unusual ways people are using their chemistry talents – what interesting jobs do you all have or want that would benefit from having a chemistry background?

Catherine (associate editor, Nature Chemical Biology)

Art for chemistry’s sake

Good news – our November issue has gone live. This one has a nice orange and black cover in time for Halloween, but more importantly, has some interesting science, including a story of sulfur sitting on a sugar sidechain, a synthesis of a smelly Streptomyces shape, and a saga about small signalling structures starting S-guanylation. We also announce some changes to the journal in our editorial; the most significant, perhaps, is that we will no longer be publishing Letters starting in 2008.

The issue also includes a commentary that talks about the intersection of science and art. In particular, David Goodsell is a practicing professor who creates artwork that, by faithfully capturing the molecular details of biomolecules, and their concentrations, locations, and functions, provides new insights into the workings of biological systems.

Along those same lines, I have been thinking recently about how people really internalize an understanding of different chemical and biological systems. Since (like many people, I assume) I learned about biology by looking at drawings that show a small nucleus and a couple of folds of the ER in a vast, otherwise empty cytosol, my first response to Dr. Goodsell’s images is always, ‘Gosh, it’s so crowded in there!’ A friend also recently passed along this YouTube video of people recreating protein synthesis in an elaborate outdoor dance (and, of course, there’s always the integrin dance which I discussed a long time ago). Finally, I will never forget an organic professor I had who taught us about the relative flexibility of 5-membered rings vs. 6-membered rings by linking his arms together at various points and flapping them all around. What explanations or images have stuck with you guys such that you will never forget about ‘random science thing X’? Or – what topics need to have their own imagery/dance/art to help you understand/remember how the process works?

Catherine (associate editor, Nature Chemical Biology)

I believe that children are our future

I only have time for a quick post, as I’m about to run off to a meeting – but I was in a baby gear/toy store yesterday, and I’m sorry to report that the children’s chemistry sets were in the “Science & Magic” section.

That pairing really threw me for a loop – I guess any sufficiently advanced technology really is indistinguishable from magic…

Joshua

Joshua Finkelstein (Senior Editor, Nature)

Reactions – Mark Green

1. What made you want to be a chemist?

It’s not really a ‘what’, more a ‘who’. My high school teacher, Mr Corkhill, who was so passionate about chemistry, he’d snarl and growl at us if we got a question wrong. His passion rubbed off on a few of us, and hence an unremarkable high school in the north of England seems to have generated quite a few graduate chemists.

2. If you weren’t a chemist and could do any other job, what would it be – and why?

If I’m allowed to lapse into fantasy, I’d like to play American football for the New York Giants – I’ve followed them passionately for the last twenty years after watching them one night when I was thirteen. A complete lack of ability in that direction means a more realistic answer would be a primary school teacher, something I’ve always wanted to do. I just enjoy teaching, especially the little ones. I tried working in science policy but it’s not for me – wearing a suit and tie (what’s the point of a tie?), going to meetings for the sake of it, clocking in, clocking out, fifteen minutes breaks, etc. I felt like I was being left behind and realised I needed to get back to a bench. I lasted five months then I got my lectureship.

3. How can chemists best contribute to the world at large?

Wow – not sure I can answer that – everything we touch and use is driven by innovative chemistry – new materials, new drugs, new technology. Each chemist thinks their own area is the key one – or they wouldn’t be doing it.

4. Which historical figure would you most like to have dinner with – and why?

My first thought was Edgar Allan Poe. Anyone that dark, moody and brooding must be fascinating company. Then I realised he’d just sit there being dark, moody and brooding, so I actually think Lawrence Taylor, ex-linebacker of the New York Giants. I always wanted to call my first child ‘Taylor’, which my wife thought was a nice name, until she realised that Taylor was a 6’4" 17 stone ex-drug addict who got paid to beat people up, so I have to rethink that.

5. When was the last time you did an experiment in the lab – and what was it?

According to my lab book, a month ago, which is quite a while ago – I’m usually in the lab once a week. I was phase-transferring some quantum dots from toluene to water for a biologist.

6. If exiled on a desert island, what one book and one CD would you take with you?

My bad music taste is legendary (Level 42, Enya, UB40, etc…), but I’m sticking to my guns, and my favourite album is Roachford’s first self entitled album. As for books, I have a stack of comfort books by my bed, ones I can pick up and read anytime – and they’re quite varied (Henry V, Wuthering Heights, His Dark Materials, Critical Mass by Philip Ball, Emergence by Steven Johnson) any of which would do, but at the moment, I’m fascinated with Freakonomics, a real eye opener.

Mark Green is in the Department of Physics at King’s College London, UK, and works on the synthesis of new nanomaterials, especially for biological applications.

Rookie Rocky: A Tale of Two Sciences

Posted on behalf of the Rookie Rocky

Chemical biology is certainly one of the fast-growing fields these days, and has become an eye-catching term. The sheer fact that high-profile journals and departments have named or renamed themselves with this phrase demonstrates the promise and potential of this interdisciplinary study. Naturally, it is not surprising to see more and more chemical biologists emerging above the horizon. Though what does chemical biology really concern? The best answer may be "it depends”. According to my humble understanding, it could cover anything that is relevant to chemistry and/or biology. However, sometimes, the categorization may affect your career development to some extent – especially to a person who just launched his/her career, this explanation becomes rather crucial. The culture of chemistry is distinct from the one of biology: in chemistry, new investigators tend to start in a different field from their previous work, while many biologists carry on projects started with former senior co-workers. What are you supposed to do if you feel that you are standing right on the borderline? To modernize Hamlet a bit: “To study chemistry or biology, that is the question.” Again, the best answer may be "it depends”. It certainly depends on the people on your tenure committee, the journals to which you send your manuscripts, and the study groups that review your grants. Just like many things in life, being vague might not be a bad strategy.

(ed’s note: we at Nature Chemical Biology have also thought about these issues. Check out this editorial for more.)

Prospective Professor: Against All Odds

[Editor’s note: another guest blogger has joined our team…]


Posted on behalf of the Prospective Professor:

After eleven years of being entrenched in higher education, I am finally making a break for it. It’s my big moment to chase my wildest professional dreams! Yes, I am looking for my first job… But instead of being deterred after many years of late night studying, failed and repeated (and repeated and repeated) experiments and even after writing that several hundred page thesis (ugh!) I find myself overwhelmingly drawn to the world in which I have been trained. That’s right, I plan to be a professor.

I am currently a post-doc working in a chemical biology lab. Earlier this year, my advisor and I decided that I was ready to start the search for my independent position. Since then, I have attempted to gather as much information as possible about the academic job search process. Despite my best efforts, I’ve only been able to accumulate a collection of rumors, hearsay, and gossip. A few weeks ago, I was lamenting to a friend about the lack of information for those of use who have chosen to pursue a professorship, “Wouldn’t it have been helpful if someone had documented this whole crazy process??” Two days later, I got an email asking me to do just that. So, I hope that I will be able to offer some useful information, tips, and impressions as I make my way to the ultimate destination – a research laboratory of my own.

The first question to ask is: how do I find the open positions? I have been most dependent upon the job search engines available on the websites of a number of journals. For example, see Nature, Chemical & Engineering News, Science, and Cell. As far as I know, these sites post the same jobs that are printed at the back of each journal. However, the online postings appear up to a week before the print version. I have also used several other websites including ChemJobs and Academic Keys.

With each job posting, I was filled with both excitement and dread. I was simultaneously amazed at how many jobs I could apply for and terrified at the thought of attempting to decide which schools were the best fit for me. There are so many variables to consider, from the reputation and funding record of the department to the location and size of the university. And then there was that quiet (and often not-so-quiet) voice inside my head saying, “But what if you don’t get a job?! You must apply for ANYTHING and EVERYTHING!”

The rumor mill tells me that for every open position there can be from 100 to 1,000 (and possibly more??) applicants. So each of us must find the balance between having confidence in our academic record and being practical about the level of competition. I’ve heard rumors of people who have applied to more than 100 positions and I’ve also heard tales of the bold scientist that applied to only one. Personally, I feel a bit like I am playing the lottery. How many jobs do I have to apply for to guarantee that I will get an offer? Not surprisingly, I’ve concluded it’s rather difficult to play the odds when I have no idea what the odds are.

In the end, I have decided to apply only for the positions that I could actually see myself accepting. This might seem obvious, but trust me, that not-so-quiet voice can be rather difficult to drown out. For me, the magic number is 43. Only time will tell if I have correctly predicted the probably of success.

(ed’s note: I also found the Chronicle of Higher Education helpful in my job searching.)