Posted on behalf of the Prospective Professor

When I started the process of finding a job, I assumed that the most challenging aspect would be the endless grilling during the interviews. I imagined that during my individual meetings with faculty members they would challenge my basic chemistry and biology knowledge, test me on my familiarity with their work and just generally attempt to check the integrity of my fundamental scientific knowledge. I expected that the proposal defense seminar (or “chalk talk”) would be filled with impossible questions, many that could only warrant the answer, “That’s an interesting question, I will have to look into that” (read as, I have NO idea).

I’m happy to report that the experience was nothing like this. People were excited to meet me and tell me about their department. Most started the meeting by saying, “Do you have any questions about our department that I could answer for you?” It was in less than 50% of the cases that we actually got around to talking about science. And while I wouldn’t call the “chalk talks” easy, I can honestly say that it was only on the rare occasion when I didn’t have an answer to a question or that I felt that people were “testing” me instead of being genuinely curious about my ideas.

It turns out that despite the huge amount of concern I poured into the interviews, I hadn’t recognized what would be the most challenging aspect of the job hunt: Deciding which job to accept.

There are so many factors to consider ranging from the quality and number of grad students, to instrumentation availability and collegiality of the faculty. I have to take into account the start-up and salary offers, teaching requirements, fundability of the institution, space availability, and the mission of the department. Next, I must decide if a chemistry department, biochemistry department or medical school would best fulfill all of my needs. And this is before I start to ponder the more personal issues such as location, cost of living, and personal relationships. How do I weigh each of these issues so that they are represented adequately in my final choice?

…

If I knew the answer to this question, I would have already made my decision!

[Editor’s note: another guest blogger has joined our team…]

Last summer, I took some time off before starting at my current position as a medicinal chemist at a large pharmaceutical company near Boston. I was out on the town (on a rather warm summer night) with my former Harvard comrades, one of whom had just successfully defended his Ph.D.

The topic of conversation naturally drifted towards everyone’s future intentions, and a familiar division became readily apparent – many of the younger graduate students intended to pursue careers in academia, while most of the older graduate students were considering other uses for a Ph.D. in chemistry. Upon hearing that my future job was in a pharmaceutical company, one of the younger graduate students exclaimed, “But you aren’t going to have control over your own research!” indicating that independence was of the utmost importance to her.

She was right: since the company pays my salary, the management decides which topics I spend my time on. But there is quite a bit of freedom in how I approach the problems they ask me to solve and there can be a great deal of creativity (and satisfaction) involved with the process. Is it any different in academia?

In my experience, not really. Most graduate students end up working on projects that their advisor is interested in, and their advisor often chooses to work on a topic that can he/she can obtain funding for (either from the government, industry, or non-profit groups). A small number of grants are “unrestricted,” but most grants are intended to be used on whatever the funding source deems particularly important. Everything works fine, until the day you have an idea that no one wants to fund. Most people get around this through a difficult compromise – they work on something that is close, but not exactly what they want to do, while a few brave souls set up labs in their garages with varying degrees of success.

Independence is a really good thing. Some amazing discoveries have come from qualified people or groups that were allowed to truly explore their own ideas, free of external bias or constraints. One clear example of the power of this concept exists in the context of popular music. During the 20th century there was an explosion of diverse musical genres that continues today. Many factors contributed to this process, but one of the most important was the fact that musical instruments and recording equipment gradually became cheaper while at the same time becoming more widely available. This made music accessible to anyone who had a desire to pick up an instrument and create music. Moreover, they could use their own recording equipment to communicate their ideas to interested parties. Today, with the advent of computers and digital recording, musicians can make home recordings of a rather high quality and easily share their songs on the internet. It is truly an exciting time to be a musician.

In terms of accessibility and expense, chemistry, and most modern sciences in general, are way behind music. A budding rock star can buy a $200 guitar at a local retailer and record songs at home, but when I think of chemistry, I think of $600,000 NMRs and $100,000 LCMS stacks installed in the hallowed halls of the worlds great schools. I consider myself extremely lucky to have access to such amazing equipment. But many scientists don’t.

While modern science is more technologically complex than music, I see no fundamental limitation to increasing the accessibility and reducing the cost of doing research. I think this is one of the great challenges facing science. Inexpensive scientific instruments would empower new scientists, give more independence to existing researchers, and lead to an increase in creativity in scientific research.

In my future columns for The Sceptical Chymist, I hope to look at chemistry and science in a new way – one that focuses more on breakthroughs in the efficiency, cost, and accessibility of the discipline rather than new pieces of expensive knowledge for assimilation. If the tools of science were made available to more people, perhaps they would be more frequently applied to problems of great interest to our society.

About the author: Jeff Johannes is a medicinal chemist at a major pharmaceutical company in the Boston area. He currently plays an Epiphone Les Paul named “Grimace.”