Career paths: Challenging convention

Professor Robert Langer, the 2015 Naturejobs Career Expo keynote speaker in Boston, shares the challenges he faced when becoming an academic entrepreneur.

Contributor Diana Cai 

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Robert Langer, David H. Koch Institute Professor at MIT and Keynote speaker at the 2015 Naturejobs Career Expo in Boston.

Robert Langer began by telling the audience about how, upon receiving his graduate degree in chemical engineering from MIT in 1974, he had job offers from 20 oil companies. “It’s not like I was that great or anything,” Langer says. He goes on to explain that the previous year had ended on a bad note for the oil market: the price of oil quadrupled in the span of four months, from $2.67 a barrel in October 1973 to $11.65 a barrel in January 1974. As a result, job opportunities for chemical engineers skyrocketed. He was ready to follow this path, until one of the engineers at a company said to him, “If you could just increase the yield of this one chemical by 0.1%, that would be wonderful!” Feeling uninspired and unable to contribute to society in that line of work, Langer decided to look for other options.

After applying to teaching positions at more than 40 colleges and failing to hear back from any of them, he asked himself, “How else can I use my chemical engineering education to help people? And I thought about medicine.” Langer eventually entered the laboratory of Judah Folkman, a professor at Harvard Medical School. Folkman was interested in angiogenesis, the process by which new blood vessels are formed. He had found that tumour growth is dependent on angiogenesis and postulated that inhibiting angiogenesis might be a way to halt tumour growth. Continue reading

Naturejobs Career Expo keynote speaker wins top engineering prize.

MIT’s Professor Robert Langer, biomedical engineer and serial entrepreneur, is this year’s sole winner of the £1m Queen Elizabeth Engineering Prize.

Professor Langer, who runs the 100-strong Langer Lab at MIT, told the Financial Times that “it is a great honour to win what is by far the biggest engineering award in the world.”

His research led to the development of drug delivery designs that would allow drugs to be released in the body over an extended period of time. His polymers were designed with long, water-filled channels that allow large molecules to gradually pass. This has specific possibilities for drugs that target conditions like cancer, mental illness and diabetes.

The prize, awarded to engineers from all over the world whose research has affected millions, if not billions of lives, is part of a UK initiative to promote engineering on a global scale, and is thought to be the equivalent of a Nobel. The 2013 award was shared by 5 people who were involved in the invention of the internet, including Sir Tim Berners-Lee. Continue reading