Data sharing: Fewer experiments, more knowledge

Data sharing will reduce the experiments needed in the lab and will increase the speed of knowledge generation by decreasing the time spent on the generation of equivalent datasets.

Guest contributor Ana Sofia Figueiredo

biological-model-naturejobs-blogI’m a postdoctoral scientist in systems biology at the University of Magdeburg, Germany. There, I build mathematical models to understand the mechanisms behind certain biological processes, such as the process of energy production by cells under extreme conditions. These mathematical models are representations of reality and some of them can be useful, although all of them are wrong. When well parameterized with data, these models give a quantitative representation and better understanding of such biological processes. Using a systems biology approach, I can do experiments in silico that are very difficult or technically impossible to do in vitro or in vivo.  However, a model is only as good as the data it incorporates.

When I have access to publicly available experimental datasets, I can plug the data into my models and, from the synergy of combining mathematical models with experimental data, learn more about the biological system I have at hands.

Sharing data, models and experimental protocols can push forward the generation of knowledge in science. Continue reading

Using maths and IT to help tackle HIV

Maths and IT play an essential role in most public health campaigns, and offer the chance for mathematicians to use their skills for social good. 

 

Global health and statistics

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Crispin Sapele is Director of Systems and Operations at CHAMP, a not for profit organisation which was set up to respond to the growing need for corporate HIV/AIDS programmes within Zambia. In December 2003 CHAMP set up a dedicated HIV hotline that offers a 24/7, 365 day counseling and information service. At CHAMP, Sapele’s role has been in planning, analyzing and evaluating the impact of such programmes, using his statistical background. Naturejobs spoke to Sapele about why maths is such a vital part of global health campaigns.

How did you get into global health?

I started off studying mathematics at the University of Zambia almost 20 years ago. I actually originally wanted to do engineering but after the first year I met one of the first mathematics professors here in Zambia and got inspired by him to do maths, so I made the switch.  After my degree, which lasted four years, I immediately got a job at the national statistics office (CSO). And with that I got my first taste of managing and running statistical health programmes, such as surveys and censuses.

How did you end up at CHAMP working on HIV prevention programmes? Continue reading

Improving work-life balance: US National Science Foundation wants your ideas

Do you have a creative suggestion for how to address issues with career-life balance in mathematics and physical sciences in the United States? If so the National Science Foundation (NSF) wants to hear from you. In an open letter published yesterday, NSF’s Edward Seidel called for the mathematics and physical sciences community to contribute to NSF’s recently launched Career-Life Balance Initiative.

Ideas specific to mathematics and physical sciences can be sent to MPSplans@nsf.gov.

General ideas for any scientific discipline can be sent to career-life-balance@nsf.gov.

Practices to improve work-life balance that NSF encourages include:

  • No-cost extensions or temporary suspensions of NSF awards due to family leave
  • Flexible start dates for NSF awards
  • Supplements for additional personnel to sustain research when principal investigators are on family leave
  • Options for remote panel participation
  • Local childcare recommendations for panellists
  • Flexible postdoctoral fellowships to accommodate dual-career placements